Products named on the most general payments in 2025
The 50 highest-ranked drugs, biologicals and devices, by general payments for program year 2025, out of $3,106,339,175 of that kind reported across the whole year. A ranking is not a judgement, and this list is a slice of the year rather than all of it.
Ranked by reported value
50 shownDownload CSV · 50 rows Free, no sign-in. Raw amounts in U.S. dollars; the second row says where the data came from.
- Pluvicto 2.1% of the year $65,308,299 · 17,080 payments
- Da Vinci Surgical System 1.6% of the year $50,329,561 · 94,673 payments
- Tecentriq 1.4% of the year $43,179,268 · 3,776 payments
- Attune 1.1% of the year $32,481,177 · 2,095 payments
- Tremfya 1% of the year $30,949,105 · 299,616 payments
- Arthrex 1% of the year $29,819,353 · 48 payments
- Dupixent 0.9% of the year $28,948,737 · 170,515 payments
- Arthrex 0.9% of the year $28,472,421 · 44 payments
- Arthrex 0.8% of the year $24,402,181 · 42 payments
- Accolade 0.8% of the year $23,909,373 · 864 payments
- Arthrex 0.7% of the year $22,543,058 · 56 payments
- General - Therapies 0.7% of the year $21,323,840 · 1,119 payments
- Mako 0.7% of the year $20,688,548 · 30,039 payments
- CD Horizon Spinal System 0.7% of the year $20,220,609 · 5,313 payments
- Invisalign 0.7% of the year $20,181,619 · 48,638 payments
- Botox 0.6% of the year $19,537,205 · 65,043 payments
- VNS Therapy Sentiva Model 1000 Generator 0.6% of the year $19,318,126 · 6,031 payments
- Davinci XI 0.6% of the year $18,327,634 · 7,187 payments
- Dupixent 0.6% of the year $18,319,971 · 146,213 payments
- Vraylar 0.6% of the year $18,104,870 · 378,411 payments
- Ingrezza 0.6% of the year $17,469,913 · 126,719 payments
- Rinvoq 0.6% of the year $17,398,537 · 279,891 payments
- Caplyta 0.5% of the year $16,858,557 · 212,166 payments
- Skyrizi 0.5% of the year $16,823,137 · 323,403 payments
- Ozempic 0.5% of the year $16,428,572 · 262,039 payments
- General - Therapies 0.5% of the year $16,070,482 · 2,495 payments
- Bimzelx 0.5% of the year $15,980,391 · 129,984 payments
- Auvelity 0.5% of the year $15,422,802 · 116,166 payments
- Other - Miscellaneous 0.5% of the year $14,408,248 · 4,441 payments
- Arthrex 0.5% of the year $14,349,971 · 32 payments
- Rezdiffra 0.5% of the year $14,136,761 · 75,724 payments
- Arthrex 0.5% of the year $13,826,774 · 24 payments
- Zepbound 0.4% of the year $12,562,864 · 186,426 payments
- Arthrex 0.4% of the year $12,211,782 · 20 payments
- Wegovy 0.4% of the year $12,130,156 · 183,294 payments
- Arthrex 0.4% of the year $11,710,706 · 25 payments
- Aequalis Perform 0.4% of the year $11,640,317 · 1,727 payments
- Arthrex 0.4% of the year $11,544,641 · 47 payments
- Imfinzi 0.4% of the year $11,413,968 · 14,496 payments
- Botox 0.4% of the year $11,374,902 · 65,778 payments
- Airsupra 0.4% of the year $11,350,180 · 165,266 payments
- Cobenfy 0.4% of the year $11,258,036 · 93,046 payments
- Arthrex 0.4% of the year $11,208,050 · 28 payments
- Lapiplasty System 1 0.4% of the year $11,075,943 · 6,023 payments
- Qulipta 0.4% of the year $11,043,147 · 299,039 payments
- Invictus OPEN 0.3% of the year $10,681,159 · 306 payments
- Nemluvio 0.3% of the year $10,649,719 · 73,234 payments
- Arthrex 0.3% of the year $10,592,299 · 8 payments
- Djo Surgical 0.3% of the year $9,856,348 · 725 payments
- Innovamatrix Ac 0.3% of the year $9,688,903 · 5,183 payments