Product Program year 2025 Source: CMS Open Payments

Kuvan

Drug Pku

NDC 68135-301-22

Open in the dashboard

General payments

$782,455

1,359 payments

Research payments

$2,681,269

507 payments

Through program year 2025, $782,455 in general payments and $2,681,269 in research payments were reported against Kuvan (Pku).

No combined total These are different kinds of money, reported under different rules. A meal and a clinical trial grant do not add up to anything meaningful, so this site does not add them.

By program year

11 rows
Year Kind Amount Payments
2025 General $355 8
2024 General $316 10
2023 General $265 11
2022 General $194,299 453
2022 Research $766,000 109
2021 General $8,203 31
2021 Research $613,226 123
2020 General $101,204 109
2020 Research $542,562 115
2019 General $477,813 737
2019 Research $759,481 160

Breakdown

Who paid General payments · program years 2019–2025
  1. BioMarin Pharmaceutical Inc. $782,455 1,359 payments
Top recipients General payments · program year 2025
  1. Elisheva Ellenberg Nurse Practitioner, Family · Detroit, MI $129 36% · 2 payments
  2. Michelle Tharp Nurse Practitioner · Jackson, MS $85 24% · 1 payment
  3. Shannon Moore Nurse Practitioner, Family · Detroit, MI $60 17% · 1 payment
  4. Heng Wang Pediatrics · Middlefield, OH $24 7% · 1 payment
  5. Vincent Cruz Clinical Genetics (M.D.) · Grand Rapids, MI $24 7% · 1 payment

The top 5 of 7 recipients; each share is of general payments naming this product in 2025.

The top 25 recipients, free in the app

Specialties paid General payments · program year 2025
  1. Nurse Practitioner, Family Nurse Practitioner $189 53% · 2 practitioners
  2. Nurse Practitioner $85 24% · 1 practitioner
  3. Pediatrics $24 7% · 1 practitioner
  4. Clinical Genetics (M.D.) Medical Genetics $24 7% · 1 practitioner
  5. Clinical Biochemical Genetics Medical Genetics $17 5% · 1 practitioner

The top 5 of 6 specialties; each share is of general payments naming this product to practitioners with a specialty in 2025. Each practitioner is counted under their primary specialty.

The top 25 specialties, free in the app

Where the money went General payments · program year 2025
  1. Michigan $212 60% · 3 recipients
  2. Mississippi $85 24% · 1 recipient
  3. Indiana $34 10% · 2 recipients
  4. Ohio $24 7% · 1 recipient

Each share is of general payments naming this product in 2025 where a state was reported.

Prescribed to Medicare patients

Part D · data year 2024

Part D claims

116

Prescriptions dispensed, refills included

Drug cost

$1,542,735

Paid at the pharmacy, in all

Prescribers

7

With 11 or more claims of it

Medicare Part D drugs matched to Kuvan, 2024
Part D drug Name match Relative to the largest Prescribers Claims Drug cost
Kuvan Sapropterin Dihydrochloride Same name 7 116 $1,542,735

Matched to this product by name; CMS does not link its files to Open Payments, so a similar name can be a different strength, form or brand. Prescriber counts include only prescribers with 11 or more claims of the drug, because CMS publishes nothing below that. Part D covers drugs dispensed to Medicare beneficiaries at a pharmacy; it does not include drugs given in a clinic or hospital, or patients with other insurance.

Largest prescribers

First 5 of 7 by claims · 2024

Two separate records. Claims come from Medicare and related payments from Open Payments. They are shown in one row because they name the same product; they do not show that a payment affected a prescription.

The prescribers with the most Part D claims of this drug in 2024
Prescriber Specialty State Claims Drug cost Related payments
Yong-Hui Jiang Medical Genetics and Genomics CT 26 $491,981 None on record
Jennifer Tiffany Amaro Nurse Practitioner PA 22 $154,973 None on record
Paul Herlan Physician Assistant CT 17 $176,999 No profile
Stefanie Yoon Nurse Practitioner TN 16 $120,943 None on record
Leah Wessenberg Nurse Practitioner OR 12 $229,999 None on record

"No profile" means the prescriber has no Open Payments record here; "None on record" means no payment naming this product in the payment year. Related payments are general payments, and one that names several products is split evenly, so an amount is payments related to the product, not money paid for it. The list is the prescribers with the most claims, up to 100 per drug.

See all 7 in the dashboard with a free account
1,359 general · 507 research

Every payment, record by record

Date, amount, who was paid and what for — filter by year and kind, or download as CSV, free, in files of 5,000 rows.

What you are looking at

Manufacturers name the drug, biological or device a payment relates to. CMS does not give products their own identifiers, so a product here is assembled from how it was reported — a brand may appear under more than one spelling, and this page covers one of them rather than the brand as a whole.

Provenance

Source: CMS Open Payments · through program year 2025

We reproduce what manufacturers reported. We do not verify, edit or correct the underlying records.

A payment record is not evidence of wrongdoing. Financial relationships between industry and medicine are legal, common and often necessary for research. Who Paid My Doc reports what was disclosed; it does not judge it.

Who Paid My Doc is independent and is not affiliated with, endorsed by or sponsored by CMS or any U.S. government agency. It is not a consumer reporting agency and this is not a consumer report; do not use it for decisions covered by the Fair Credit Reporting Act.

How to dispute or correct a record