Medical Doctor Program year 2025 Reported 2019–2025 Source: CMS Open Payments, 2026 publication

Ralph Defronzo

Endocrinology, Diabetes & Metabolism San Antonio, TX Medical Doctor

NPI 1851408843 CMS profile 265075

701 S Zarzamora St, San Antonio, TX 78207

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General payments

$879,625

509 records reported · program years 2019–2025

Research payments

$0

Paid to them · None reported · program years 2019–2025

Ownership & investment interest

$0

None reported

Research they led as principal investigator

$3,879,962 paid to institutions, not to them · program years 2019–2025

Through program year 2025, Ralph Defronzo of San Antonio, TX is reported in the CMS Open Payments database as having received $879,625 across 509 general payments and $0 in research payments paid to them. Separately, studies naming them as principal investigator received $3,879,962 in research payments, paid to institutions rather than to them.

No combined total General, research and ownership are kept apart. Each is reported under its own rules, and ownership is not money that moved at all but the value of a stake held. A meal, a clinical trial grant and a shareholding do not add up to anything meaningful, so this site does not add them. The principal-investigator line is research money paid to institutions for studies they led — not to them — and is not added to anything either.

General payments for this record sit in the 99th percentile of Endocrinology, Diabetes & Metabolism profiles with reported payments. Percentile describes the distribution, not the conduct.

By program year

7 rows
Year Kind Relative to this record's peak year Amount Records
2025 General $112,578 62
2024 General $142,981 71
2023 General $100,208 50
2022 General $76,211 54
2021 General $81,276 47
2020 General $179,452 85
2019 General $186,919 140

Beside peers

Year by year, beside peers General payments · among profiles paid that year
  • Ralph Defronzo
  • Endocrinology, Diabetes & Metabolism median
  • Middle half of Endocrinology, Diabetes & Metabolism
  • National median

In program year 2025, general payments to Ralph Defronzo were reported at $112,578. Among 5,868 Endocrinology, Diabetes & Metabolism profiles paid that year, the median was $507 and the middle half received between $135 and $1,838.

Show as a table
Year Ralph Defronzo Endocrinology, Diabetes & Metabolism median Middle half National median
2019 $186,919 $494 $123–$2,253 $163
2020 $179,452 $335 $85–$1,841 $114
2021 $81,276 $398 $88–$1,981 $132
2022 $76,211 $364 $88–$1,568 $149
2023 $100,208 $420 $113–$1,614 $160
2024 $142,981 $440 $121–$1,646 $164
2025 $112,578 $507 $135–$1,838 $169

Breakdown

Who paid General payments · program years 2019–2025
  1. AstraZeneca Pharmaceuticals LP $328,521 234 payments
  2. Corcept Therapeutics $167,596 73 payments
  3. Novo Nordisk Inc $150,000 87 payments
  4. Hikma Pharmaceuticals USA $66,846 19 payments
  5. Regeneron Pharmaceuticals, Inc. $34,135 37 payments
  6. Alnylam Pharmaceuticals Inc. $20,880 3 payments
  7. Janssen Pharmaceuticals, Inc $14,375 6 payments
  8. Novo Nordisk AS $14,085 7 payments
  9. Pfizer Inc. $12,800 4 payments
  10. GlaxoSmithKline, LLC. $9,833 4 payments
  11. Other $60,554 35 payments

Every payment, record by record

What the payments were for General payments · program years 2019–2025
  1. Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $467,768 137 payments
  2. Consulting Fee $254,525 74 payments
  3. Travel and Lodging $122,908 156 payments
  4. Honoraria $21,920 7 payments
  5. Food and Beverage $12,485 134 payments
  6. Education $19 1 payment
Products named General payments · program years 2019–2025
  1. FARXIGA $318,139 209 payments
  2. Korlym $167,596 73 payments
  3. Ozempic $54,630 36 payments
  4. Victoza $35,141 16 payments
  5. INVOKANA $14,375 6 payments
  6. GLYXAMBI $9,060 2 payments
  7. KIDNEYINTELX BLOOD COLLECTION CONVENIENCE KIT $8,688 3 payments
  8. Kerendia $8,036 8 payments
  9. JARDIANCE $7,744 4 payments
  10. Tresiba $7,100 5 payments
  11. Other $4,619 22 payments

A payment can name more than one product, so these amounts overlap and do not add up to the general-payment figure.

Records

509 reported

Every payment, record by record

Date, company, amount, what it was for and the product named — filter by year, kind and company, or download as CSV.

Other Endocrinology, Diabetes & Metabolism in Texas

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What this means

U.S. law requires drug and medical device manufacturers to report payments and transfers of value they make to physicians and teaching hospitals. The Centers for Medicare & Medicaid Services publishes that record each year. This page shows what was reported about this person, and nothing else.

An ownership interest is different from the other two. It is not a payment: it is a stake — shares, options, a partnership holding — that a physician or an immediate family member held in a manufacturer during that year. The figure shown is what the stake was reported to be worth.

Research payments frequently pass through a clinician to the institution running a trial, and rarely represent personal income. They should be read differently from general payments.

Provenance

Source: CMS Open Payments · through program year 2025

Data current to program year 2025, from CMS's 2026 publication.

We reproduce what manufacturers reported. We do not verify, edit or correct the underlying records.

A payment record is not evidence of wrongdoing. Financial relationships between industry and medicine are legal, common and often necessary for research. Who Paid My Doc reports what was disclosed; it does not judge it.

Who Paid My Doc is independent and is not affiliated with, endorsed by or sponsored by CMS or any U.S. government agency. It is not a consumer reporting agency and this is not a consumer report; do not use it for decisions covered by the Fair Credit Reporting Act.

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