Medical Doctor Program year 2025 Reported 2019–2025 Source: CMS Open Payments, 2026 publication

John Isaac

Interventional Cardiology Houston, TX Medical Doctor

NPI 1295799005 CMS profile 486366

6560 Fannin St, Ste 620, Houston, TX 77030

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General payments

$1,779,317

3,268 records reported · program years 2019–2025

Research payments

$0

Paid to them · None reported · program years 2019–2025

Ownership & investment interest

$0

None reported

Through program year 2025, John Isaac of Houston, TX is reported in the CMS Open Payments database as having received $1,779,317 across 3,268 general payments and $0 in research payments paid to them.

No combined total General, research and ownership are kept apart. Each is reported under its own rules, and ownership is not money that moved at all but the value of a stake held. A meal, a clinical trial grant and a shareholding do not add up to anything meaningful, so this site does not add them.

General payments for this record sit in the 99th percentile of Interventional Cardiology profiles with reported payments. Percentile describes the distribution, not the conduct.

By program year

7 rows
Year Kind Relative to this record's peak year Amount Records
2025 General $214,376 383
2024 General $199,612 420
2023 General $140,389 396
2022 General $283,273 486
2021 General $273,090 451
2020 General $233,187 415
2019 General $435,390 717

Beside peers

Year by year, beside peers General payments · among profiles paid that year
  • John Isaac
  • Interventional Cardiology median
  • Middle half of Interventional Cardiology
  • National median

In program year 2025, general payments to John Isaac were reported at $214,376. Among 6,173 Interventional Cardiology profiles paid that year, the median was $1,092 and the middle half received between $366 and $3,019.

Show as a table
Year John Isaac Interventional Cardiology median Middle half National median
2019 $435,390 $1,097 $329–$3,048 $163
2020 $233,187 $473 $161–$1,480 $114
2021 $273,090 $677 $233–$1,827 $132
2022 $283,273 $978 $333–$2,724 $149
2023 $140,389 $1,136 $382–$2,986 $160
2024 $199,612 $1,181 $395–$3,326 $164
2025 $214,376 $1,092 $366–$3,019 $169

Breakdown

Who paid General payments · program years 2019–2025
  1. Esperion Therapeutics, Inc. $355,721 413 payments
  2. Amgen Inc. $318,809 523 payments
  3. AstraZeneca Pharmaceuticals LP $215,189 284 payments
  4. Boehringer Ingelheim Pharmaceuticals, Inc. $127,835 166 payments
  5. E.R. Squibb & Sons, L.L.C. $125,497 258 payments
  6. Sanofi-Aventis U.S. LLC $118,009 150 payments
  7. Amarin Pharma Inc. $87,213 166 payments
  8. Janssen Pharmaceuticals, Inc $85,233 176 payments
  9. Lilly USA, LLC $78,502 106 payments
  10. Regeneron Healthcare Solutions, Inc. $58,364 101 payments
  11. Other $208,945 925 payments

Every payment, record by record

What the payments were for General payments · program years 2019–2025
  1. Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $1,430,498 562 payments
  2. Travel and Lodging $193,038 928 payments
  3. Consulting Fee $72,745 25 payments
  4. Food and Beverage $70,955 1,744 payments
  5. Honoraria $12,000 3 payments
  6. Education $82 6 payments
Products named General payments · program years 2019–2025
  1. NEXLETOL $355,721 413 payments
  2. NEXLIZET $354,671 365 payments
  3. Repatha Cardiology $191,030 337 payments
  4. REPATHA Cardiovascular $127,690 184 payments
  5. JARDIANCE $112,598 135 payments
  6. FARXIGA $102,897 151 payments
  7. BRILINTA $100,347 111 payments
  8. PRALUENT $100,081 110 payments
  9. CAMZYOS $93,660 144 payments
  10. XARELTO $85,214 175 payments
  11. Other $485,243 1,632 payments

A payment can name more than one product, so these amounts overlap and do not add up to the general-payment figure.

Prescribing to Medicare patients

Part D · data year 2024 · 90 drugs

Part D claims

18,211

Median for Cardiology: 2,533

Drug cost

$4,746,991

Median for Cardiology: $485,213

Branded share of claims

33.3%

Median for Cardiology: 25.7%

Drugs this doctor was counted under in Medicare Part D 2024, by drug cost
Drug Type Relative to their largest Claims Drug cost
Eliquis Apixaban Brand 881 $1,115,667
Repatha Sureclick Evolocumab Brand 1,403 $1,104,081
Entresto Sacubitril/Valsartan Brand 256 $397,344
Multaq Dronedarone Hcl Brand 138 $263,820
Xarelto Rivaroxaban Brand 177 $238,661
Vascepa Icosapent Ethyl Brand 255 $219,917
Jardiance Empagliflozin Brand 165 $219,290
Praluent Pen Alirocumab Brand 302 $206,886
Farxiga Dapagliflozin Propanediol Brand 154 $176,325
Nexlizet Bempedoic Acid/Ezetimibe Brand 181 $168,812

The 10 drugs with the highest cost, of 90 counted.

Drug cost is what was paid for the drugs at the pharmacy — by Medicare, the patient and others — and is not money to the prescriber. Medicare Part D only: drugs dispensed to Medicare beneficiaries. A drug with fewer than 11 claims for this prescriber is not published, so a missing drug does not mean zero. The medians are for the 18,782 Part D prescribers listed as Cardiology; they describe a distribution and say nothing about conduct.

Billing to Medicare

Part B · data year 2024 · 73 billing codes

Paid by Medicare

$1,788,203

Of which drugs: $9,654

Medicare patients

1,253

Average age 76

Services billed

9,530

639 women, 614 men among their patients

Share of this provider's Medicare patients with each condition
Condition among their Medicare patients Relative to the most common Share of patients
High blood pressure 75%
Ischemic heart disease 66%
Arthritis 49%
Diabetes 30%
Atrial fibrillation 29%
Chronic kidney disease 27%
Heart failure 20%
Cancer 19%
Drugs given in the clinic that this provider billed Medicare Part B for
Drug given in the clinic Where Patients Services Paid by Medicare
Injection, regadenoson, 0.1 mg J2785 Office 437 1,752 $9,654

Medicare Part B only: services billed to Medicare. Rows covering fewer than 11 beneficiaries are not published. Only drugs given in the clinic are itemised here; the rest of what this provider billed is in the total above.

Payments and prescribing

First 5 of 26 products · payments 2024

Two separate records. The payments come from Open Payments and the claims from Medicare. They are set side by side because they name the same product; they do not show that a payment affected a prescription.

Products this doctor was paid in connection with in 2024, beside Medicare claims for the same product
Product Paid by Related payments Part D claims Part B services
Arcalyst
$45,032 — —
Repatha
$37,192 1,423 —
JARDIANCE
$26,834 165 —
NEXLETOL
$25,253 15 —
NEXLIZET
$25,196 181 —

A dash means Medicare published no figure for this doctor and product — fewer than 11 claims, or the product is not covered under that part — which is not the same as none. Payments are general payments only; one that names several products is split evenly between them, so an amount is payments related to the product, not money paid for it.

See more in the dashboard: 25 with a free account, all 26 with Patron

Records

3,268 reported

Every payment, record by record

Date, company, amount, what it was for and the product named — filter by year, kind and company, or download as CSV.

Other Interventional Cardiology in Texas

Related records

What this means

U.S. law requires drug and medical device manufacturers to report payments and transfers of value they make to physicians and teaching hospitals. The Centers for Medicare & Medicaid Services publishes that record each year. This page shows what was reported about this person, and nothing else.

An ownership interest is different from the other two. It is not a payment: it is a stake — shares, options, a partnership holding — that a physician or an immediate family member held in a manufacturer during that year. The figure shown is what the stake was reported to be worth.

Research payments frequently pass through a clinician to the institution running a trial, and rarely represent personal income. They should be read differently from general payments.

Provenance

Source: CMS Open Payments · through program year 2025

Data current to program year 2025, from CMS's 2026 publication.

We reproduce what manufacturers reported. We do not verify, edit or correct the underlying records.

A payment record is not evidence of wrongdoing. Financial relationships between industry and medicine are legal, common and often necessary for research. Who Paid My Doc reports what was disclosed; it does not judge it.

Who Paid My Doc is independent and is not affiliated with, endorsed by or sponsored by CMS or any U.S. government agency. It is not a consumer reporting agency and this is not a consumer report; do not use it for decisions covered by the Fair Credit Reporting Act.

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